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Vitamin D deficiency has been shown to alter lung structure and function in a new study in young mice.

The new study, conducted by researchers in Australia, offers the first concrete evidence linking vitamin D deficiency with deficits in lung function and altered lung structure.

“The results of this study clearly demonstrate that vitamin D deficiency alters lung growth, resulting in lower lung volume and decrements in lung function,” said Graeme Zosky, a research fellow at the Telethon Institute for Child Health Research in Subiaco, Australia.

“This is the first direct mechanistic evidence showing that vitamin D deficiency alters lung development, which may explain the association between obstructive lung disease and levels of vitamin D.”

To conduct their study, the researchers used a mouse model of vitamin D deficiency and evaluated lung responses of two-week-old mice, comparing them to control mice without vitamin D deficiency to determine what, if any, effects the deficiency may have caused in the growth, structure or function of the lungs.

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